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The 'sickening touch' spell is a low level necromancer spell, typically used before combat. When cast, the target's hands become weapons of sickness for a short period of time. When the target strikes an enemy in battle with his hands, the spell discharges and poisons and sickens the enemy.
This spell, like Burning Hands and Shocking Grasp, requires the use of your hands to trigger the effects. This means you must have at least one hand free to trigger the spell, but you can still wield a weapon as long as your off-hand is free.