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Rotting Sphere is a powerful necromancer spell that sends a rather unpleasant mass of ethereal mouths to bite the target, scouring it with poison.
Rotting Sphere deals poison damage over a period of time to the target, and additionally will deal more damage the larger the target is. It is unknown if this damage will stack with itself or if recasting the spell simply refreshes it.
Rotting Sphere has a charge up time before the spell actually hits, so using Haste to reduce it is very helpful. You should also be cautious using it so that you are not stuck in the casting time when you suddenly need to flee, heal, or resummon a minion.